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What is Chloroquine?
Chloroquine is primarily helpful in preventing and treating malaria in areas where malaria stays sensitive to its effects. Specific types of malaria, complicated cases, and resistant strains usually require different or additional medication.
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How to take Chloroquine?
Take Chloroquine precisely as per the doctor’s prescription. Read carefully and follow all the directions on the prescription label and medication guides.
Usual adult dosage for malaria prevention:
300 mg base (500 mg salt) orally one time a week
Usual adult dosage for malaria (less than 60 kg):
- First dose- 10 mg/kg base (16.7 mg/kg salt) orally
- Second dose (six hours after the first one)- 5 mg/kg base (8.3 mg/kg salt) orally
- Third dose (24 hours after the first one)- 5 mg/kg base (8.3 mg/kg salt) orally
- Fourth dose (36 hours after the first one)- 5 mg/kg base (8.3 mg/kg salt) orally
- Total dosage- 25 mg/kg base (41.7 mg/kg salt) in three days
Usual adult dosage for amebiasis:
- 600 mg base (1 g salt) orally once a day for two days, followed by 300 mg base (500 mg salt) orally once a day for at least two to three weeks
What to know before taking Chloroquine?
Before taking Chloroquine, tell each of your medical healthcare providers if you are allergic to it or hydroxychloroquine or if you have other allergies. This product may cause allergic reactions or other issues because of its inactive ingredients.
Avoid taking it if you have a complicated medical history, especially of:
- Vision or eye problems;
- A specific enzyme problem (G6PD- glucose-6-phosphate dehydrogenase deficiency);
- Kidney disease;
- Liver disease;
- Skin problems (psoriasis);
- Regular alcohol consumption;
- Porphyria (a specific blood disorder); or
- Seizures
Benefits of using Chloroquine
Chloroquine is beneficial in the prevention and treatment of malaria. It also helps treat amebiasis (infection caused by amoebae).
Chloroquine belongs to the antimalarial class of drugs. Talk to your doctor to get the maximum benefit of this medicine while traveling to malaria areas.
This medicine is not approved to treat coronavirus infection (COVID-19) unless you have enrollment in a study. Your doctor will help you to know about the risks and benefits.
Side effects of Chloroquine
Common side effects to Chloroquine may include:
- Nausea;
- Headache;
- Vomiting;
- Diarrhea; or
- Abdominal cramps
Tell the doctor right away if you have severe side effects. That may include:
- Slow heartbeat;
- Severe dizziness;
- Irregular or fast heartbeat;
- Fainting;
- seizures;
- Heart failure symptoms such as swollen ankles or feet, shortness of breath, sudden or unusual weight gain, unusual tiredness;
- Mood swings or mental changes such as depression, anxiety, hallucinations, rare thoughts of suicide;
- Hearing changes such as hearing loss, ringing in the ears;
- Easy bleeding or bruising;
- Infection signs such as fever, sore throat;
- Symptoms of liver disease such as stomach or abdominal pain (severe), dark urine, yellowing of eyes or skin;
- Muscle weakness;
- Hair or skin color changes;
- Hair loss; or
- Unwanted or uncontrolled movements
Chloroquine may cause hypoglycemia (low blood sugar). Tell your doctor promptly if you develop low blood sugar symptoms such as shaking, sweating, blurred vision, dizziness, hunger, or tingly feeling in your hands and feet. If you have diabetes, ensure to check your blood sugar level regularly.
This drug may result in severe vision problems such as sensitivity to light, vision changes (such as blurred vision, light flashes or streaks, missing areas of the image, difficulty reading).
In rare cases, a severe allergic reaction may occur. Signs of an allergic reaction may include rash, swelling or itching of face, throat, or tongue, trouble breathing, severe dizziness.
It is not a complete list of side effects, and others may occur. Take your doctor’s advice regarding side effects. Report side effects to FDA at 1-800-FDA-1088.
How Chloroquine works?
Chloroquine is an antimalarial drug. It helps treat malaria by killing the disease-causing parasites.
The working of this drug to treat rheumatoid arthritis or lupus erythematosus is not fully understood. However, medical researchers believe that this medicine affects your immune system’s working, which may benefit lupus erythematosus and rheumatoid arthritis cases.
This medicine is not approved to treat coronavirus infection (COVID-19) unless you have enrollment in a study. Your doctor will help you to know about the risks and benefits.
What to avoid while using Chloroquine?
Chloroquine may cause impair your reactions and cause blurred vision. Avoid driving a vehicle or performing hazardous activities until you know this medicine’s effect on you.
Avoid taking Kaopectate (kaolin-pectate) or antacid within four hours before or after you take Chloroquine.